High dietary phosphorus and renal indicators in cats

Nine cats developed glucosuria and microalbuminuria under high-phosphorus feeding; creatinine clearance decreased.

Evidence Library

Abstract-based review · 2018

High dietary phosphorus and renal indicators in cats

Nine cats developed glucosuria and microalbuminuria under high-phosphorus feeding; creatinine clearance decreased.

CatFeeding or challenge experiment

Review scope

Abstract-based review. Full methods, complete statistical results and product equivalence have not been appraised. This is research context, not an individual feeding or treatment recommendation.

Study question and design

13 healthy adult cats. A high-phosphorus diet providing approximately five times maintenance requirements versus balanced control feeding for 29 days.

Main findings

Nine cats developed glucosuria and microalbuminuria under high-phosphorus feeding; creatinine clearance decreased.

Limitations and applicability

The tested formulation does not establish equal risk for every phosphorus source or a universal safe threshold.

Ingredients investigated

Multi-ingredient formulations

Phosphorus

Multi ingredient · cat. 13 healthy adult cats.

Tested form: High-phosphorus experimental diet; exact phosphate salts not established in the reviewed abstract. Dose: Approximately five times the maintenance requirement (Dietary phosphorus relative to maintenance requirement; oral feeding. Exact concentration not established in the reviewed abstract). Duration: 29 days. Comparator: Balanced control diet.

Measured finding: Nine of 13 cats developed glucosuria and microalbuminuria; creatinine clearance decreased during the high-phosphorus feeding period.

Limitations: Small healthy-cat experiment and short duration. Phosphate source and calcium-to-phosphorus ratio are not established in the abstract; these findings cannot be applied using the ingredient name alone.

This ingredient was part of a combined formulation; the study does not isolate its contribution.

Abstract reviewed · Checked 2 October 2026 · Evidence.pet study summary · Primary source

Evidence.pet interpretation

Apply this result only within its species, preparation and study conditions. An ingredient listing alone does not establish that a commercial product reproduces the tested intervention.

Funding and conflicts

The authors declared no conflicts of interest. Funding was not established from the reviewed abstract.

Ingredient references

Phosphorus.

These are research references. The tested form, dose and formulation must be matched before using a result to support a product claim.

Source

Dobenecker B; Webel A; Reese S; Kienzle E. Effect of a high phosphorus diet on indicators of renal health in cats. Journal of Feline Medicine and Surgery. 2018. DOI: 10.1177/1098612X17710589.

Primary source record (PMID 28569079) · Publisher DOI

Reviewed 2 October 2026 · Next review 2 January 2027.